Effect of Increased Abdominal Pressure on Cytokines (IL1 beta, IL6, TNF alpha), C-reactive Protein (CRP), Free Radicals (NO, MDA), and Histology

Ozmen, Mahir; Zulfikaroglu, Baris; Col, Cavit; Cinel, Ismail; Isman, Ferruh; Cinel, Leyla; Besler, Tanju

doi:10.1097/sle.0b013e31819cdda7

Effect of Increased Abdominal Pressure on Cytokines (IL1 beta, IL6, TNF alpha), C-reactive Protein (CRP), Free Radicals (NO, MDA), and Histology

Ozmen M. M., Zulfikaroglu B., Col C., Cinel I., Isman F. K., Cinel L., ...Daha Fazla

SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES, cilt.19, sa.2, ss.142-147, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: 2
Basım Tarihi: 2009
Doi Numarası: 10.1097/sle.0b013e31819cdda7
Dergi Adı: SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.142-147
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: It is generally accepted that proinflammatory mediators, including cytokines, are responsible for the metabolic changes associated with injury. Recent clinical and experimental studies have also shown that the laparoscopic procedures actually produce ischemia-reperfusion injury in the organs by oxygen-derived free radicals. This Study aimed to assess the effect of different insufflation pressures and laparotomy on tissue response by comparing the proinflammatory cytokines, C-reactive protein, and serum and tissue levels of oxygen-derived free radicals.