Intake Duration of Anthocyanin-Rich New Zealand Blackcurrant Extract Affects Cardiovascular Responses during Moderate-Intensity Walking But Not at Rest

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Sahin M. A., BİLGİÇ P., Montanari S., Willems M. E. T.

JOURNAL OF DIETARY SUPPLEMENTS, cilt.20, sa.3, ss.428-443, 2023 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1080/19390211.2021.2005214
  • Dergi Adı: JOURNAL OF DIETARY SUPPLEMENTS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.428-443
  • Anahtar Kelimeler: Anthocyanin, blackcurrant, blood flow, blood pressure, cardiovascular responses, exercise, flavonoid, polyphenols, DISEASE MORTALITY, FLAVONOID INTAKE, IN-VITRO, IDENTIFICATION, ACTIVATION, JUICE, RISK
  • Hacettepe Üniversitesi Adresli: Evet

Özet

We examined effects of intake duration of New Zealand blackcurrant (NZBC) extract on cardiovascular responses during supine rest and moderate-intensity walking. Recreationally active men (n = 15, age: 24 +/- 6 yr, BMI: 24.7 +/- 4.3 kg center dot m(-2)) volunteered in a randomized, cross-over design. One metabolic equivalent (1-MET) was measured (3.97 +/- 0.66 mL center dot kg(-1)center dot min(-1)) and an incremental walking test was performed to individualize speed at 4 (n = 3) or 5 (n = 12) METs for the 30-min walk (5.7 +/- 0.7 km center dot hr(-1)). NZBC extract (210 mg of anthocyanins) was taken with breakfast for 7 and 14 days, with a 14-days washout. The final dose was ingested 2-hr before recording of the cardiovascular responses (Portapres Model-2). At rest, %changes at 7- and 14-days intake were observed for stroke volume (+6.8% (trend), p = 0.065; +8.5%, p = 0.012), cardiac output (+10.1%, p = 0.007; +8.5%, p = 0.013), total peripheral resistance (-12.0%, p = 0.004; -13.1%, p = 0.011), diastolic (-5.7%, p = 0.045; -9.7%, p = 0.015) and mean arterial pressure (-4.4%, p = 0.040; -7.2%, p = 0.029), but without intake duration effect. During walking, %changes at 7- and 14-days intake were observed for stroke volume (+7.7% (trend), p = 0.063; +9.9%, p = 0.006), cardiac output (+8.7%, p = 0.037; +10.1%, p = 0.007), diastolic blood pressure (-6.2%, p = 0.042; -10.6%, p = 0.001), and total peripheral resistance (-9.6%, p = 0.042; -13.5%, p = 0.005) but without intake duration effect. During walking, %changes at 14-days were observed only for mean arterial pressure (-6.4%, p = 0.018) and arterio-venous oxygen difference (-7.9%, p = 0.019). NZBC extract affects cardiovascular responses at rest and during moderate-intensity exercise with 7- and 14-day intake. Only during moderate-intensity exercise, a longer intake of NZBC extract was required for an effect on some cardiovascular responses.