Management of Inflammatory Bowel Disease and Pregnancy using Prophylactic Low Dose Low Molecular Weight Heparin and Corticosteroids


Beksac K., ÖRGÜL G., CAN G. S. , Oktem A., KAV T., BEKSAÇ M. S.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, vol.11, no.11, 2017 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 11
  • Publication Date: 2017
  • Doi Number: 10.7860/jcdr/2017/24683.10900
  • Journal Name: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
  • Journal Indexes: Emerging Sources Citation Index, Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals

Abstract

The circulating nonspecific immune complexes, complement system peptides and auto-antibodies may induce inflammatory/ thrombotic events at the placenta and impairment of endometrial receptivity as well as disturbed fetal perfusion in Inflammatory Bowel Disease (IBD) cases. The aim of the case series was to assess the effect of "Low Molecular Weight Heparin" (LMWH) and Low Dose Corticosteroids (LDC) against possible thromboembolic and inflammatory processes happening at the maternal fetal interface and to assess their efficiency in pregnancy outcomes.