Successful renal transplantation in a child with ANCA-associated microscopic polyangiitis


Besbas N. , Ozaltin F., Tinaztepe K., Gucer S., Ozen S., Bakkaloglu M., ...Daha Fazla

PEDIATRIC NEPHROLOGY, cilt.18, ss.696-699, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 7
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1007/s00467-003-1114-4
  • Dergi Adı: PEDIATRIC NEPHROLOGY
  • Sayfa Sayıları: ss.696-699

Özet

Crescentic glomerulonephritis (CGN) is a clinicopathologic entity which is characterized by severe renal dysfunction of rapid onset with glomerular crescents. Type III CGN is associated with the absence of glomerular immune complex deposition (pauci-immune) and is associated with antineutrophil cytoplasmic antibody (ANCA). Microscopic polyangiitis and idiopathic pauci-immune necrotizing glomerulonephritis (NCGN) are strongly associated with ANCA directed against myeloperoxidase (anti-MPO). We describe here an unusual pediatric patient with MPO-ANCA-associated rapidly progressive glomerulonephritis (RPGN), emphasizing the management and outcome of the disease.