Selenium status in Turkey - Possible link between status of selenium, iodine, antioxidant enzymes and oxidative DNA damage

Giray B., Hincal F.

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, vol.259, no.3, pp.447-451, 2004 (SCI-Expanded) identifier identifier


Measured (n=36, 51 mug/day) and estimated (n=274, 44 mug/day) dietary daily intake of selenium in Turkey is low compared to the RDA value of 55 mug Se/day. When the existence of high prevalence of iodine deficiency in most part of the country is considered, adequate level of dietary Se becomes more important. We have found recently that high iodine-deficient goitrous children had lower Se levels and antioxidant enzyme (AOE) activities, and higher levels of DNA base lesions than non-goitrous controls.