Simultaneous surface registration of ictal and interictal SPECT and magnetic resonance images for epilepsy studies

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MUMCUOGLU E., NAR F., YARDIMCI Y., KOCAK U., ERGUN E., SALANCI B., ...More

NUCLEAR MEDICINE COMMUNICATIONS, vol.27, no.1, pp.45-55, 2006 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 27 Issue: 1
• Publication Date: 2006
• Doi Number: 10.1097/01.mnm.0000189775.75743.0b
• Journal Name: NUCLEAR MEDICINE COMMUNICATIONS
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.45-55
• Hacettepe University Affiliated: Yes

Abstract

Background Subtraction of ictal and interictal single photon emission computed tomography (SPECT) images is known to be successful in localizing the seizure focus in the pre-surgical evaluation of patients with partial epilepsy. A computer-aided methods for producing subtraction ictal SPECT co-registered to the magnetic resonance image (MRI) (the SISCOM method) is commonly used. The two registrations involved in SISCOM are (1) between the ictal-interictal SPECT images, which was shown to be the more critical, and (2) between the ictal image and MRI.