A reduction of sleep spindles heralds seizures in focal epilepsy

TEZER F. I., REMI J., ERBİL N., NOACHTAR S., SAYGI S.

CLINICAL NEUROPHYSIOLOGY, vol.125, no.11, pp.2207-2211, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 125 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1016/j.clinph.2014.03.001
  • Journal Name: CLINICAL NEUROPHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2207-2211
  • Keywords: Sleep, Epilepsy, Epilepsy surgery, Sleep spindle, Seizure prediction, INTERICTAL EPILEPTIFORM DISCHARGES, FREQUENCY ACTIVITY, OSCILLATIONS
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: Sleep has profound effects on epilepsy. It may alter the occurrence of interictal discharges (IEDs) and seizures. Vice versa, an active epilepsy changes sleep. Sleep spindles are typically associated with an increase of IEDs. We examined whether seizures change the number and power of spindles preceding nightly seizures.