HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

Castellsague, Xavier; Alemany, Laia; Quer, Miquel; Halec, Gordana; Quiros, Beatriz; Tous, Sara; Clavero, Omar; Alos, Llucia; Biegner, Thorsten; Szafarowski, Tomasz; Alejo, Maria; Holzinger, Dana; Cadena, Enrique; Claros, Edith; Hall, Gillian; Laco, Jan; Poljak, Mario; Benevolo, Maria; Kasamatsu, Elena; Mehanna, Hisham; Ndiaye, Cathy; Guimera, Nuria; Lloveras, Belen; Leon, Xavier; Ruiz-Cabezas, Juan; Alvarado-Cabrero, Isabel; Kang, Chang-Suk; Oh, Jin-Kyoung; Garcia-Rojo, Marcial; Iljazovic, Ermina; Ajayi, Oluseyi; Duarte, Flora; Nessa, Ashrafun; Tinoco, Leopoldo; Duran-Padilla, Marco; Pirog, Edyta; Viarheichyk, Halina; Morales, Hesler; Costes, Valerie; Felix, Ana; Germar, Maria; Mena, Marisa; Ruacan, Arzu; Jain, Asha; Mehrotra, Ravi; Goodman, Marc; Lombardi, Luis; Ferrera, Annabelle; Malami, Sani; Albanesi, Estela; Dabed, Pablo; Molina, Carla; Lopez-Revilla, Ruben; Mandys, Vaclav; Gonzalez, Manuel; Velasco, Julio; Bravo, Ignacio; Quint, Wim; Pawlita, Michael; Munoz, Nubia; de Sanjose, Silvia; Bosch, F.

doi:10.1093/jnci/djv403

HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

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Castellsague X., Alemany L., Quer M., Halec G., Quiros B., Tous S., ...More

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, vol.108, no.6, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 108 Issue: 6
Publication Date: 2016
Doi Number: 10.1093/jnci/djv403
Journal Name: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe University Affiliated: No

Abstract

Background: We conducted a large international study to estimate fractions of head and neck cancers (HNCs) attributable to human papillomavirus (HPV-AFs) using six HPV-related biomarkers of viral detection, transcription, and cellular transformation.