Development of albumin macroinitiator for polymers to use in DNA origami coating

Bilir A., Emul E., SAĞLAM N.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.50, sa.5, ss.1461-1469, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.3906/sag-2001-245
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1461-1469
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background/aim: DNA nanostructures have many advantages over polymers and lipid based drug delivery agents such as biodegradability and biocompatibility. However their transfection rates and stability still limits their widely use in nanomedicine. In this study highly versatile and straightforward albumin coating preparation method is showed for DNA nanostructures.