A case of Crimean-Congo haemorrhagic fever successfully treated with therapeutic plasma exchange and ribavirin

Kurnaz F., Metan G. , Coskun R., KAYNAR L., Eser B., DOĞANAY M.

TROPICAL DOCTOR, cilt.41, ss.181-182, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 41 Konu: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1258/td.2011.100470
  • Sayfa Sayıları: ss.181-182


Crimean-Congo haemorrhagic fever (CCHF) has become an important problem in certain parts of the world. Cytokine storm plays a critical role in the pathogenesis of CCHF. Early diagnosis, supportive therapy and invasive monitoring are the cornerstones of the management of CCHF. Ribavirin is active against CCHF virus in vitro, however, evidence of clinical efficacy is still conflicting. Here, we describe a patient successfully recovered from CCHF with a combination of plasma exchange and ribavirin therapy.