Sclerotherapy with bleomycin does not adversely affect facial nerve function in children with cervicofacial cystic lymphatic malformation


KARAVELIOGLU A., TEMUÇİN Ç. M. , TANYEL F. C. , ÇİFTÇİ A. Ö. , Senocak M. E. , KARNAK İ.

JOURNAL OF PEDIATRIC SURGERY, vol.45, no.8, pp.1627-1632, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 8
  • Publication Date: 2010
  • Doi Number: 10.1016/j.jpedsurg.2009.12.014
  • Title of Journal : JOURNAL OF PEDIATRIC SURGERY
  • Page Numbers: pp.1627-1632

Abstract

Background and Purpose: Sclerotherapy with bleomycin sulfate (BS) is currently used in the management of cervicofacial cystic lymphatic malformations in children. Neurotoxic adverse effects of BS after intraventricular or intracavitary administration have been reported; however, the effects of intralesionally administered BS on the adjacent peripheral neural structures have not been previously investigated. The authors conducted a clinical experimental study to evaluate facial nerve function in children who have undergone BS sclerotherapy for cervicofacial cystic lymphatic malformation.