Synthesis of new 2,3-dihydrofuran-3-one derivative and its reactions with some primary amines


Ungoren S., Sacmaci M., Akcamur Y.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.41, no.2, pp.151-155, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 2004
  • Doi Number: 10.1002/jhet.5570410203
  • Title of Journal : JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Page Numbers: pp.151-155

Abstract

The Wittig reaction of 2,3-dihydro-4-(4-methoxybenzoyl)-5-(4-methoxyphenyl)-furan-2,3-dione (1) with methyl (triphenylphosphoranylidene)acetate (2) stereo- and regioselectively afforded methyl (Z)-[2,3-dihydro-4-(4-methoxybenzoyl)-5 - (4-methoxyphenyl) - 3 -oxofuran-2-ylidene]acetate (3) in good yield. The reactions of 3 with primary amines (4a-k) gave corresponding 1-substituted 2,3 -dihydro-1H-pyrrol-3 -ones (5a-k).