Effects of freezing of gait on balance in patients with Parkinson’s disease


Korkusuz S., Seçkinoğulları B., Özcan A., Demircan E. N., Çakmaklı G. Y., ARMUTLU K., ...More

Neurological Research, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2022
  • Doi Number: 10.1080/01616412.2022.2149510
  • Journal Name: Neurological Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Keywords: balance, gait, movement disorders, Neurological rehabilitation, Parkinson’s disease
  • Hacettepe University Affiliated: Yes

Abstract

© 2022 Informa UK Limited, trading as Taylor & Francis Group.Objectives: The aim of the study was to evaluate the effects of freezing of gait (FOG) on static and dynamic balance. Methods: Twenty patients with Parkinson’s disease with and without FOG [PD+FOG (68,6±6,39 years) and PD-FOG group (70,6±4,57 years)] and 10 healthy individuals (68,4±4,92 years) with similar demographic characteristics were included in the study. Balance was compared between the three groups. Balance was evaluated with clinical tests Limits of stability (LoS) and body sway were measured using the E-LINK FP3 Force Plate and the Korebalance Balance Evaluation System, which measure the balance in static and dynamic conditions. Center of pressure (COP) change and average sway velocity were evaluated with the Zebris RehaWalk system. Results: Total and subscale scores of the Unified Parkinson’s Disease Rating Scale were significantly higher in the PD+FOG group (p<0.05). The balance test results for both groups were similar (p>0.05). The PD+FOG group performed worse on the computerized static balance tests, the COP analysis, and the dynamic balance total score than the other two groups (p<0.05). The PD+FOG group had significantly greater sustained weight deviation than the healthy controls (p<0.05). Patients with Parkinson’s disease had a lower LoS in the posterior direction than healthy controls (p<0.05). Discussion: FOG affects the dynamic balance more negatively than the static balance. In addition, FOG reduces LoS in the posterior direction and increases body sway in the anterior-posterior direction, which can lead to falls. Keywords: Center of pressure, Freezing of gait, Limits of stability, Parkinson’s disease, Postural Balance.