Is double-blinding possible while administering fluids in the intensive care unit?


Durukan A. B. , Gurbuz H. A. , Yorgancioglu C., DURUKAN A. B. , Gurbuz H. A. , Tavlasoglu M.

CARDIOVASCULAR JOURNAL OF AFRICA, vol.24, no.4, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Letter
  • Volume: 24 Issue: 4
  • Publication Date: 2013
  • Title of Journal : CARDIOVASCULAR JOURNAL OF AFRICA

Abstract

The publication by Alavi SM et al. highlights a subject with an ongoing debate, namely the 'crystalloid-colloid and colloid-colloid use following cardiac surgery'. They designed a randomised, double-blind clinical trial and compared the effects of three different solutions; 0.9% Ringer's lactate, 4% gelatin and 6% hydroxyethyl starch (HES) solution. They concluded that the HES solution was better in terms of the volume-expanding effect; lower amounts were required compared to the other two solutions, and short-term renal functions were better.