A histopathologicai investigation on the effect of systemic administration of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the rat mandible


Kaynak D., Meffert R., Bostanci H., Gunhan O., Ozkaya Ö.

JOURNAL OF PERIODONTOLOGY, cilt.74, sa.9, ss.1348-1354, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Sayı: 9
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1902/jop.2003.74.9.1348
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1348-1354
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: The present study was designed to assess histopathologically whether the systemic administration of aminobisphosphonate (alendronate), 0.5 mg/kg body weight, is effective in preventing alveolar bone resorption following mucoperiosteal flap surgery, and whether alendronate modulates tissue factors.