A histopathologicai investigation on the effect of systemic administration of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the rat mandible
JOURNAL OF PERIODONTOLOGY, cilt.74, sa.9, ss.1348-1354, 2003 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 74 Sayı: 9
- Basım Tarihi: 2003
- Doi Numarası: 10.1902/jop.2003.74.9.1348
- Dergi Adı: JOURNAL OF PERIODONTOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1348-1354
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: The present study was designed to assess histopathologically whether the systemic administration of aminobisphosphonate (alendronate), 0.5 mg/kg body weight, is effective in preventing alveolar bone resorption following mucoperiosteal flap surgery, and whether alendronate modulates tissue factors.