A histopathologicai investigation on the effect of systemic administration of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the rat mandible


Kaynak D., Meffert R., Bostanci H., Gunhan O., Ozkaya Ö.

JOURNAL OF PERIODONTOLOGY, cilt.74, ss.1348-1354, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 74 Konu: 9
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1902/jop.2003.74.9.1348
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Sayfa Sayıları: ss.1348-1354

Özet

Background: The present study was designed to assess histopathologically whether the systemic administration of aminobisphosphonate (alendronate), 0.5 mg/kg body weight, is effective in preventing alveolar bone resorption following mucoperiosteal flap surgery, and whether alendronate modulates tissue factors.