Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

Demir, AS; Akhmedov, IM; Sesenoglu, Ö; Alptürk, Onur; Apaydin, S; Gerçek, Z; Ibrahimzade, NEZİRE

doi:10.1039/b008317h

Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

Demir A., Akhmedov I., Sesenoglu Ö., Alptürk O., Apaydin S., Gerçek Z., ...Daha Fazla

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, sa.10, ss.1162-1167, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2001
Doi Numarası: 10.1039/b008317h
Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Index Chemicus (IC)
Sayfa Sayıları: ss.1162-1167
Hacettepe Üniversitesi Adresli: Evet

Özet

The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.