Measurement of ethyl glucuronide in vitreous humor with liquid chromatography-mass spectrometry

KETEN A., TÜMER A. R., BALSEVEN-ODABASI A.

FORENSIC SCIENCE INTERNATIONAL, vol.193, pp.101-105, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 193
  • Publication Date: 2009
  • Doi Number: 10.1016/j.forsciint.2009.09.018
  • Journal Name: FORENSIC SCIENCE INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.101-105
  • Keywords: Ethanol, Ethyl glucuronide, Vitreous humor, Postmortem, ALCOHOL-CONSUMPTION, POSTMORTEM BLOOD, IN-VITRO, ETHANOL, AUTOPSY, PHOSPHATIDYLETHANOL, ANTEMORTEM, SAMPLES, LIVER
  • Hacettepe University Affiliated: Yes

Abstract

Background: It is important to detect alcohol intake in postmortem investigations. However it can be difficult to interpret the results of alcohol analysis in putrefied corpses. To avoid this difficulty, there have been studies on detection of ethyl glucuronide (EtG), a non-oxidative metabolite of ethyl alcohol. The aim of this study was investigate EtG levels in vitreous humor (VH), a valuable material in postmortem investigations, and to compare VH EtG levels with blood and urine EtG levels.