The effect of inorganic salt type and concentration on hydrophilic drug loading into microspheres using the emulsion/solvent diffusion method

YAG, Goksu; ÇALIŞ, SEMA; Arica-Yegin, BETÜL

doi:10.3109/03639045.2012.763139

The effect of inorganic salt type and concentration on hydrophilic drug loading into microspheres using the emulsion/solvent diffusion method

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YAG G., ÇALIŞ S., Arica-Yegin B.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol.40, no.3, pp.390-397, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 40 Issue: 3
Publication Date: 2014
Doi Number: 10.3109/03639045.2012.763139
Journal Name: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.390-397
Hacettepe University Affiliated: Yes

Abstract

Aim: In order to avoid gastric irritation caused by tolmetin sodium (TS), gastro resistant Eudragit (R) S 100 microsphere formulations were prepared with the emulsion/solvent diffusion method.