A case of interleukin-12 receptor beta-1 deficiency with recurrent leishmaniasis

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Atıf İçin Kopyala

Sanal O., Turkkani G., Gumruk F., Yel L., Secmeer G., Tezcan I., ...Daha Fazla

PEDIATRIC INFECTIOUS DISEASE JOURNAL, cilt.26, sa.4, ss.366-368, 2007 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 26 Sayı: 4
• Basım Tarihi: 2007
• Doi Numarası: 10.1097/01.inf.0000258696.64507.0f
• Dergi Adı: PEDIATRIC INFECTIOUS DISEASE JOURNAL
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.366-368
• Hacettepe Üniversitesi Adresli: Evet

Özet

Interleukin-12 receptor beta-1 (IL-12R beta 1) defect is generally associated with selective susceptibility to weakly pathogenic mycobacteria and Salmonella species. Patients rarely experience infections caused by other organisms. We report a 5-year-old patient with IL-12R beta 1 deficiency who developed recurrent visceral leishmaniasis 6 months apart. The patient responded to lyposomal amphotericin B treatment reasonably well.