Differential renal function estimation by dynamic renal scintigraphy: influence of background definition and radiopharmaceutical

Caglar M., Gedik G. K., KARABULUT E.

NUCLEAR MEDICINE COMMUNICATIONS, vol.29, no.11, pp.1002-1005, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 11
  • Publication Date: 2008
  • Doi Number: 10.1097/mnm.0b013e32830978af
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1002-1005
  • Hacettepe University Affiliated: Yes


Objectives Differential renal function (DRF) calculation with Tc-diethylenetriamine-pentaacetic acid (DTPA) or mercaptoacetyltriglycine (MAGO is gaining clinical importance in the evaluation of patients with ureteropelvic junction obstruction with hydronephrosis (HN). Although many decisions regarding surgery are based on the functional changes detected by serial diuretic renography, the reliability of DRF estimation has been questioned. Factors such as the correction of nonrenal activity included in the renal region of interest (background subtraction) and immature function resulting in poor renal extraction may cause unusual elevation in the differential function. The aim of this study is to evaluate the impact of the radiopharmaceutical and positioning of the background on the DRIP.