Systemic and large local reactions during subcutaneous grass pollen immunotherapy in children

Gur Cetinkaya P., KAHVECİ M., Esenboga S., Karaatmaca B., Soyer Ö., ŞEKEREL B. E. , ...More

PEDIATRIC ALLERGY AND IMMUNOLOGY, vol.31, no.6, pp.643-650, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.1111/pai.13261
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.643-650
  • Keywords: adverse reactions, allergic rhinitis, children, pollen, subcutaneous immunotherapy, ALLERGEN IMMUNOTHERAPY, FATAL REACTIONS, RISK-FACTORS, EXTRACTS, IMPACT, INJECTIONS, RHINITIS
  • Hacettepe University Affiliated: Yes


Background Subcutaneous immunotherapy (SCIT) is the allergen-specific curative treatment of allergic rhinitis. Adverse effects, most of which are local, can be observed during the immunotherapy. These adverse effects have been reported more frequently during the pollen season. The purpose of this study was to estimate the rate of local, large local, and systemic reactions during the treatment, to determine the relationship between adverse reactions and the season in which these reactions occur, as well as the risk factors for adverse reactions during the grass pollen-specific SCIT treatment in children.