Evaluation of the Possible Role of miRNAs in Chemical Allergen Potency

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ANLAR H. G., Galbiati V., Corsini E., Basaran N.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.17, no.4, pp.452-456, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.4274/tjps.galenos.2019.25349
  • Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.452-456
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: MicroRNAs (miRNAs) are short, endogenous noncoding RNA molecules that can bind to certain parts of target mRNAs, thereby regulating gene expression. Studies showed that miRNAs could be upor downregulated in different allergic skin conditions but there is still need for further studies. The aim of this study was to investigate the expression of miRNAs in response to the common contact allergen Bandrowski's base (BB), the principal allergen in patients reacting to p-phenylenediamine (PPD).