Evaluation of the Possible Role of miRNAs in Chemical Allergen Potency

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ANLAR H. G., Galbiati V., Corsini E., Basaran N.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.17, sa.4, ss.452-456, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tjps.galenos.2019.25349
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.452-456
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives: MicroRNAs (miRNAs) are short, endogenous noncoding RNA molecules that can bind to certain parts of target mRNAs, thereby regulating gene expression. Studies showed that miRNAs could be upor downregulated in different allergic skin conditions but there is still need for further studies. The aim of this study was to investigate the expression of miRNAs in response to the common contact allergen Bandrowski's base (BB), the principal allergen in patients reacting to p-phenylenediamine (PPD).