Evaluation of the Possible Role of miRNAs in Chemical Allergen Potency


ANLAR H. G. , Galbiati V., Corsini E., Basaran N.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.17, sa.4, ss.452-456, 2020 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Konu: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tjps.galenos.2019.25349
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Sayfa Sayıları: ss.452-456

Özet

Objectives: MicroRNAs (miRNAs) are short, endogenous noncoding RNA molecules that can bind to certain parts of target mRNAs, thereby regulating gene expression. Studies showed that miRNAs could be upor downregulated in different allergic skin conditions but there is still need for further studies. The aim of this study was to investigate the expression of miRNAs in response to the common contact allergen Bandrowski's base (BB), the principal allergen in patients reacting to p-phenylenediamine (PPD).