Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial

Bluemcke I. , Coras R., Busch R. M. , Morita-Sherman M., Lal D., Prayson R., ...Daha Fazla

EPILEPSIA, 2021 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası:
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1111/epi.16899
  • Dergi Adı: EPILEPSIA


Objective Focal cortical dysplasia (FCD) is a major cause of difficult-to-treat epilepsy in children and young adults, and the diagnosis is currently based on microscopic review of surgical brain tissue using the International League Against Epilepsy classification scheme of 2011. We developed an iterative histopathological agreement trial with genetic testing to identify areas of diagnostic challenges in this widely used classification scheme.