Lower CYP2C9 activity in Turkish patients with Beh double dagger et's disease compared to healthy subjects: a down-regulation due to inflammation?


Goktas M. T. , Hatta F., KARACA O., KALKISIM S., KILIC L. , AKDOĞAN A. , ...Daha Fazla

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, cilt.71, ss.1223-1228, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 71 Konu: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00228-015-1899-7
  • Dergi Adı: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • Sayfa Sayıları: ss.1223-1228

Özet

Background We previously reported on a Swedish patient with Beh double dagger et's disease (BD) who was an ultra-rapid metaboliser of drugs catalysed by CYP2C9. Was this extreme metabolism caused by the disease?