Type 1 sirenomelia in one of male twins, with imperforate anus in the other male twin

Akbiyik F., Balci S., Akkoyun I., Aktas D., Cakmak O.

CLINICAL DYSMORPHOLOGY, vol.9, no.3, pp.227-229, 2000 (SCI-Expanded) identifier

  • Publication Type: Article / Letter
  • Volume: 9 Issue: 3
  • Publication Date: 2000
  • Doi Number: 10.1097/00019605-200009030-00015
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.227-229
  • Hacettepe University Affiliated: Yes


The etiology of sirenomelia sequence is still obscure. The role of maternal diabetes and a vascular steal phenomenon have been discussed [Gurakan et al. (1996) Turk J Pediatr 38:393-397]. Discordant monozygotic twin sirenomelia has been commonly reported but only rarely in dizygotic twins. The family of the presented twins had a high risk of diabetes mellitus. One of the twins has type 1 sirenomelia and the other had only an imperforate anus. Clin Dysmorphol 9: 227-229 (C) 2000 Lippincott Williams & Wilkins.