Atıf İçin Kopyala
Yazici S., Kim S., Busby J., He J., Thaker P., Yokoi K., ...Daha Fazla
PROSTATE, cilt.65, sa.3, ss.203-215, 2005 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
65
Sayı:
3
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Basım Tarihi:
2005
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Doi Numarası:
10.1002/pros.20283
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Dergi Adı:
PROSTATE
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.203-215
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Anahtar Kelimeler:
prostate cancer, EGF-R and VEGF-R phosphorylation, antivascular therapy, RECEPTOR TYROSINE KINASE, CELL LUNG-CANCER, MICROVASCULAR HYPERPERMEABILITY, CLINICAL-SIGNIFICANCE, EGF RECEPTOR, TUMOR-CELLS, EXPRESSION, ANGIOGENESIS, PROGRESSION, BLOCKADE
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Hacettepe Üniversitesi Adresli:
Evet
Özet
BACKGROUND. Androgen-independent prostate cancer (PCa) may be susceptible to modulation of the tumor microenvironment. We determined whether a dual tyrosine kinase inhibitor (AEE788) of the epidermal growth factor receptor (EGF-R) and vascular endothelial growth factor receptor (VEGF-R) combined with chemotherapy can produce therapy of human PCa in nude mice.