Correlation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats


AKTEPE O. H., ŞAHİN T. K., GÜNER G., GÜVEN D. C., YETER H. H., KURTULAN O., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.32, no.12, pp.1049-1056, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.5152/tjg.2021.20899
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1049-1056
  • Keywords: AOM, colon cancer, Ki-67, prognosis, THSD7A, FOCAL ADHESION KINASE, DOMAIN-CONTAINING 7A, COLORECTAL-CANCER, TISSUES
  • Hacettepe University Affiliated: Yes

Abstract

Background: Thrombospondin type 1 domain-containing 7A (THSD7A) has emerged as a new potential molecular tool for multiple tumors since that THSD7A was detected to be expressed in various malignant tumor types including colorectal cancer (CRC). Thus, we investigated the correlation between THSD7A expression and pathologic determinants of azoxymethane (AOM)-induced CRC in a rat model.