Correlation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats

AKTEPE O. H., ŞAHİN T. K., GÜNER G., GÜVEN D. C., YETER H. H., KURTULAN O., ...Daha Fazla

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.32, sa.12, ss.1049-1056, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 12
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/tjg.2021.20899
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1049-1056
  • Anahtar Kelimeler: AOM, colon cancer, Ki-67, prognosis, THSD7A, FOCAL ADHESION KINASE, DOMAIN-CONTAINING 7A, COLORECTAL-CANCER, TISSUES
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Thrombospondin type 1 domain-containing 7A (THSD7A) has emerged as a new potential molecular tool for multiple tumors since that THSD7A was detected to be expressed in various malignant tumor types including colorectal cancer (CRC). Thus, we investigated the correlation between THSD7A expression and pathologic determinants of azoxymethane (AOM)-induced CRC in a rat model.