Angiotensin-converting enzyme genotype predicts valve damage in acute rheumatic fever

Atalar E., Tokgozoglu S., Alikasifoglu M., Ovunc K., Aksoyek S., Kes S., ...Daha Fazla

JOURNAL OF HEART VALVE DISEASE, cilt.12, sa.1, ss.7-10, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2003
  • Dergi Adı: JOURNAL OF HEART VALVE DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.7-10
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background and aim of the study: The genetic basis for host susceptibility to subsequent valve damage and scarring is not well defined in patients with a history of acute rheumatic fever (ARF). A high angiotensin-converting enzyme (ACE) activity has been demonstrated in valve tissue; hence, the study aim was to determine whether the ACE-DD genotype was a predisposing factor to heart valve damage after ARF attack.