Efficacy of tenofovir in adefovir-experienced patients compared with treatment-naive patients with chronic hepatitis B


KESKİN O. , Ormeci A. C. , BARAN B., KABAÇAM G., TÜZÜN A. E. , KARATAYLI E., ...Daha Fazla

ANTIVIRAL THERAPY, cilt.19, ss.543-550, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3851/imp2732
  • Dergi Adı: ANTIVIRAL THERAPY
  • Sayfa Sayıları: ss.543-550

Özet

Background: Tenofovir (TDF) has similar antiviral efficacy in both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients. Data on TDF use in patients with adefovir (ADV) resistance is inconsistent. The aim of our study was to assess antiviral efficacy of TDF against nucleoside analogue-naive (NN) and ADV-resistant (ADV-R) CHB and suboptimal responders to ADV (ADV-S).