Flavonol Glycosides and Iridoids from Asperula lilaciflora
HELVETICA CHIMICA ACTA, vol.97, no.11, pp.1571-1576, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 97 Issue: 11
- Publication Date: 2014
- Doi Number: 10.1002/hlca.201400065
- Journal Name: HELVETICA CHIMICA ACTA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1571-1576
- Hacettepe University Affiliated: Yes
Abstract
A new flavonol glycoside, quercetin 3-O-[6'''-O-3,5-dihydroxycinnamoyl-beta-glucopyranosyl-(1 -> 2)]-beta-galactopyranoside (named lilacifloroside; 1) and a new iridoid 2 (named asperulogenin), were isolated from the aerial parts of Asperula lilaciflora in addition to eight known secondary metabolites, i.e., quercetin, kaempferol, quercetin 3-O-beta-glucopyranosyl-(1 -> 2)-beta-galactopyranoside, quercetin 3-O-beta-glucopyranosyl-(1 -> 2)-arabinopyranoside, asperuloside, deacetylasperulosidic acid, asperulosidic acid methyl ester, and chlorogenic acid. The structures were elucidated on the basis of extensive 1D- and 2D-NMR experiments as well as MS data. Compound 1 contains the rare 3,5-dihydroxycinnamoyl moiety in its structure. This work constitutes the first phytochemical study of the title plant.