Flavonol Glycosides and Iridoids from Asperula lilaciflora


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Kirmizibekmez H., Bardakci H., Masullo M., Kamburoglu O., Eryilmaz G., AKAYDIN G., ...More

HELVETICA CHIMICA ACTA, vol.97, no.11, pp.1571-1576, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 97 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1002/hlca.201400065
  • Journal Name: HELVETICA CHIMICA ACTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1571-1576
  • Hacettepe University Affiliated: Yes

Abstract

A new flavonol glycoside, quercetin 3-O-[6'''-O-3,5-dihydroxycinnamoyl-beta-glucopyranosyl-(1 -> 2)]-beta-galactopyranoside (named lilacifloroside; 1) and a new iridoid 2 (named asperulogenin), were isolated from the aerial parts of Asperula lilaciflora in addition to eight known secondary metabolites, i.e., quercetin, kaempferol, quercetin 3-O-beta-glucopyranosyl-(1 -> 2)-beta-galactopyranoside, quercetin 3-O-beta-glucopyranosyl-(1 -> 2)-arabinopyranoside, asperuloside, deacetylasperulosidic acid, asperulosidic acid methyl ester, and chlorogenic acid. The structures were elucidated on the basis of extensive 1D- and 2D-NMR experiments as well as MS data. Compound 1 contains the rare 3,5-dihydroxycinnamoyl moiety in its structure. This work constitutes the first phytochemical study of the title plant.