Research Information System
LANCET, vol.355, no.9204, pp.605-609, 2000 (SCI-Expanded)
Background Sight-threatening eye involvement is a serious complication of Behcet's disease. Extraocular complications such as arthritis, vascular occlusive disorders, mucocutaneous lesions, and central-nervous-system disease may lead to morbidity and even death. We designed a prospective study in newly diagnosed patients without previous eye disease to assess whether prevention of eye involvement and extraocular manifestations, and preservation of visual acuity are possible with combination treatments with and without interferon alfa-2b.