Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth

Guncu G. N. , Caglayan F. , Dincel A., Bozkurt A. , Saygi S. , Karabulut E.

JOURNAL OF PERIODONTOLOGY, cilt.77, sa.12, ss.2005-2010, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 77 Konu: 12
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1902/jop.2006.060103
  • Sayfa Sayıları: ss.2005-2010


Background: Gingival enlargement is one of the side effects associated with the administration of phenytoin. The mechanism by which phenytoin induces gingival enlargement is not well understood. This study was conducted to investigate the relationship between plasma and gingival crevicular fluid (GCF) phenytoin concentrations and the degree of gingival overgrowth in patients with similar gingival and plaque indices and also to determine the risk factors for gingival enlargement.