Effects of levobupivacaine and bupivacaine on intracellular calcium signaling in cultured rat dorsal root ganglion neurons

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Ozcan M., AYAR A., Alcin E., Ozcan S., Kutlu S.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, vol.30, no.2, pp.115-120, 2010 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 30 Issue: 2
• Publication Date: 2010
• Doi Number: 10.3109/10799891003630614
• Journal Name: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.115-120
• Hacettepe University Affiliated: No

Abstract

Bupivacaine and levobupivacaine have been shown to be effective in the treatment of pain as local anesthetics, although the mechanisms mediating their antinociceptive actions are still not well understood. The aim of this study was to investigate the effects of bupivacaine and levobupivacaine on intracellular calcium ([Ca