Concise total syntheses of (+/-)-noruleine and (+/-)-uleine

Patir S., Erturk E.

ORGANIC & BIOMOLECULAR CHEMISTRY, vol.11, no.17, pp.2804-2810, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 17
  • Publication Date: 2013
  • Doi Number: 10.1039/c3ob40180d
  • Journal Name: ORGANIC & BIOMOLECULAR CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2804-2810
  • Hacettepe University Affiliated: Yes

Abstract

The first total synthesis of (+/-)-noruleine and a concise synthesis of (+/-)-uleine have been accomplished via the DDQ mediated dehydrogenative cyclization of a tetrahydrocarbazole derivative bearing a non-substituted amide functionality to prepare the key azocino[4,3-b]indole precursor.