Expression of glutathione-S-transferases isoenzymes and p53 in exfoliated human bladder cancer cells

Oguztuzun, Serpil; Sezgin, Yasemin; Yazici, MUSTAFA; Firat, Pinar; Ozhavzali, Muzeyyen; Ozen, Haluk

doi:10.1016/j.urolonc.2009.08.001

Expression of glutathione-S-transferases isoenzymes and p53 in exfoliated human bladder cancer cells

Oguztuzun S., Sezgin Y., Yazici S., Firat P., Ozhavzali M., Ozen H.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, cilt.29, sa.5, ss.538-544, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 29 Sayı: 5
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.urolonc.2009.08.001
Dergi Adı: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.538-544
Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives: This study investigates the usefulness of glutathione-S-transferases (GST) isoenzymes and p53 immunostaining as a marker of malignancy in urinary cytology, and evaluates their potential effect in increasing diagnostic accuracy in a series of urine cytologic samples. They are also correlated with cytopathology diagnosis and histopathologic diagnosis.