Expression of water channel aquaporin-4 during experimental syringomyelia: Laboratory investigation

Aghayev K., Bal E., Rahimli T., Mut M. , Balci S., Vrionis F., ...Daha Fazla

Journal of Neurosurgery: Spine, cilt.15, ss.428-432, 2011 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 15 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3171/2011.5.spine10303
  • Dergi Adı: Journal of Neurosurgery: Spine
  • Sayfa Sayıları: ss.428-432


Object. Aquaporins (aqp) are protein channels providing water transport across cell membranes. The main member of this family expressed in the CNS is aqp-4. The pattern and amount of expression of this channel suggest a dominant role in bulk water movement into the nervous tissue. It has also been shown to play a role in several water balance disorders in the CNS. In this study, the authors investigated the possible role of aqp-4 in syringomyelia.