Akademik Veri Yönetim Sistemi
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.39, sa.2, ss.201-205, 2014 (SCI-Expanded)
Objective: Previously we have shown a counter-regulation between cholinesterases (ChEs) through both anti-sense Butyrylcholinesterase (BChE) transfection and knock-down by siRNAs in R28 cells. In course of this counter-regulation, the status of the cell growth- and differentiation-related signaling pathways PKC and ERK were also changed. Down-regulation of BChE led to an increased PKC-alpha expression. Here, we demonstrate that this interaction between ChEs and PKC is reciprocal.