Parvovirus 1319 infection presenting as pre-B-cell acute lymphoblastic leukemia: A transient and progressive course in two children
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.26, no.10, pp.689-692, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 26 Issue: 10
- Publication Date: 2004
- Doi Number: 10.1097/01.mph.0000136454.01329.38
- Journal Name: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.689-692
- Hacettepe University Affiliated: Yes
Abstract
Parvovirus B19 is the causative agent of various forms Of hematologic diseases such as aplastic crisis in patients with hemolytic anemia, aplastic anemia, hypoplastic anemia, and idiopathic thrombocytopenic purpura. In addition, parvovirus B19 infection may precede or be associated with acute lymphoblastic leukemia (ALL). The authors present two cases of parvovirus B19 infection and bone marrow infiltration with pre-B-cell lymphoblasts; one patients was diagnosed as having ALL, and the other patient, with neurologic findings, showed total resolution of the blastic morphology and phenotype.