Atıf İçin Kopyala
Kuyumcu A., Akyol A., Buyuktuncer Z., OZMEN M. M., BESLER H. T.
NUTRITION JOURNAL, cilt.14, 2015 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
14
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Basım Tarihi:
2015
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Doi Numarası:
10.1186/1475-2891-14-4
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Dergi Adı:
NUTRITION JOURNAL
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Anahtar Kelimeler:
Major abdominal surgery, N-acetyl cystein, Plasma amino acids, Oxidant parameters, TOTAL PARENTERAL-NUTRITION, RANDOMIZED CONTROLLED-TRIAL, LENGTH-OF-STAY, GASTROINTESTINAL CANCER, ATRIAL-FIBRILLATION, AMINO-ACIDS, ACETYLCYSTEINE SUPPLEMENTATION, ANTIOXIDANT DEFENSES, REPERFUSION INJURY, HUMAN ERYTHROCYTES
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Hacettepe Üniversitesi Adresli:
Evet
Özet
Background: Increased levels of reactive oxygen species during and after surgery may affect inflammatory response, post-operative adhesion molecule formation, and hemodynamic stability. The glutathione redox cycle is an important regulator in oxidative stress and its reduced forms scavenge free radicals. N-acetyl cysteine, a precursor of reduced glutathione, is considered as a potentially therapeutic wide spectrum agent in clinical practice. We therefore examined whether N-acetyl cysteine improves some biochemical parameters in cancer patients undergoing major abdominal surgery.