Evaluation of histologic changes in the urinary tract of hypercalciuric rats

AKIL I., KAVUKCU S., INAN S., YILMAZ O., Atilla P., ISLEKEL H., ...More

PEDIATRIC NEPHROLOGY, vol.21, no.11, pp.1681-1689, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 11
  • Publication Date: 2006
  • Doi Number: 10.1007/s00467-006-0216-1
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1681-1689
  • Keywords: hypercalciuria, normocalcemic hypercalciuria, uroepithelium, bladder, ureter, rat, IDIOPATHIC HYPERCALCIURIA, INFECTION, CHILDREN, CHILDHOOD, CRYSTALS, CELLS
  • Hacettepe University Affiliated: Yes

Abstract

Idiopathic hypercalciuria (IH) has been speculated to have a predisposing role in the development of urinary tract infection (UTI), due to the uroepithelial cell damage it leads to. In this study, we aimed to investigate the effects of hypercalciuria on the bladder, ureters, and kidneys in rats with experimentally induced hypercalciuria.