High-flow oxygen therapy for treatment of acute migraine: A randomized crossover trial

Singhal, MEHMET; Maas, Matthew; Goldstein, Joshua; Mills, Brittany; Chen, David; Ayata, Cenk; Kacmarek, Robert; Topcuoglu, Mehmet

doi:10.1177/0333102416651453

High-flow oxygen therapy for treatment of acute migraine: A randomized crossover trial

Singhal A. B., Maas M. B., Goldstein J. N., Mills B. B., Chen D. W., Ayata C., ...More

CEPHALALGIA, vol.37, no.8, pp.730-736, 2017 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 37 Issue: 8
Publication Date: 2017
Doi Number: 10.1177/0333102416651453
Journal Name: CEPHALALGIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.730-736
Keywords: Migraine, normobaric oxygen therapy, headache, SPREADING DEPRESSION, HYPERBARIC-OXYGEN, CLUSTER HEADACHE, TURNING-POINT, HYPEROXIA, HYPOXIA, DEPOLARIZATIONS, PATHOPHYSIOLOGY, GUIDELINES, DRUGS
Hacettepe University Affiliated: Yes

Abstract

Background: Impaired oxygen utilization and cerebrovascular dysfunction are implicated in migraine. High-flow oxygen is effective in cluster headache and has shown promise in animal models of migraine, but has not been adequately studied in patients with migraine.