Reduced anaerobic and aerobic performance in children with primary ciliary dyskinesia


SIMSEK S., Inal-Ince D. , ÇAKMAK A. , Emiralioglu N. , CALIK-KUTUKCU E. , SAĞLAM M. , ...Daha Fazla

EUROPEAN JOURNAL OF PEDIATRICS, cilt.177, ss.765-773, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 177 Konu: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00431-018-3121-2
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRICS
  • Sayfa Sayıları: ss.765-773

Özet

Primary ciliary dyskinesia (PCD) restricts lifestyle and increases morbidity. The aim of the study was to investigate anaerobic and aerobic performance in children with PCD and their healthy counterparts. Thirty-one children with PCD and 29 age- and sex-matched healthy subjects were studied. Pulmonary function, hand grip strength (HGS), quadriceps strength (QMS), physical activity, anaerobic capacity (muscle power sprint test), and aerobic performance (modified shuttle walk test (MSWT)) were determined. Pulmonary function, HGS, QMS, mean anaerobic power (MAP), and MSWT distance in PCD were significantly lower than those of healthy subjects (p < 0.05). In PCD, the MAP was significantly correlated with age, FEV1, and the mean kcal for 3 days (p < 0.05), and age was its independent predictor (p < 0.05). The MSWT distance was significantly related to gender and weight (p < 0.05), and gender was selected as its independent predictor (p < 0.05). In healthy controls, the MAP was significantly associated with age, gender, FVC, FEV1, HGS, QMS, and the mean kcal for three days (p < 0.05). The MSWT distance was significantly related to weight and body mass index in healthy group (p < 0.05).