BOSENTAN, A NON-SPECIFIC ENDOTHELIN ANTAGONIST, STIMULATES FRACTURE HEALING

Muratli, Hasan; KORKUSUZ, PETEK; KORKUSUZ, PETEK; Bicimoglu, Ali; Ercan, Z.

doi:10.1142/s1016237207000045

BOSENTAN, A NON-SPECIFIC ENDOTHELIN ANTAGONIST, STIMULATES FRACTURE HEALING

Muratli H. H., KORKUSUZ P., KORKUSUZ P., Bicimoglu A., Ercan Z. S.

BIOMEDICAL ENGINEERING-APPLICATIONS BASIS COMMUNICATIONS, cilt.19, sa.1, ss.37-46, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: 1
Basım Tarihi: 2007
Doi Numarası: 10.1142/s1016237207000045
Dergi Adı: BIOMEDICAL ENGINEERING-APPLICATIONS BASIS COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.37-46
Hacettepe Üniversitesi Adresli: Evet

Özet

It is assumed that bosentan, a non-selective ET-1 receptor antagonist, will enhance fracture healing. The aim of this prospective randomized controlled study was to investigate the effects of transcutaneous bosentan administration into diaphyseal bone fractures using radiology, histology, prostaglandin E-2 (PGE(2)) and leukotrien C-4 (LTC4) activity measurements.