Secondary hemophagocytic lymphohistiocytosis in Turkish children

Gurgey A., Secmeer G., Tavil B., Ceyhan M., Kushkonmaz B. B. , Cengiz B., ...Daha Fazla

PEDIATRIC INFECTIOUS DISEASE JOURNAL, cilt.24, ss.1116-1117, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 12
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1097/01.inf.0000190043.48182.31
  • Sayfa Sayıları: ss.1116-1117


Between January 1998 and January 2005, a total of 18 children 2 weeks-72 months of age were diagnosed as having secondary hemophagocytic lymphohistiocytosis. The frequency of secondary hemophagocytic lymphohistiocytosis among total hospitalized patients during this period was 0.05% (18 of 34,250). Of the 18 patients, 8 (44.5%) had bacterial infections; cytomegalovirus and Epstein-Barr virus infections were present in 5 (28%) and 1 (5.5%), patient, respectively. Leishmaniasis was diagnosed in 2 patients (11%), and herpes simplex virus was diaganosed in 2 patients (11%). Six patients died during treatment, and 1 patient was lost to follow-up. The survival rate was 61%.