The purpose of this paper was to present the management of a rarely encountered transposition anomaly involving the mandibular permanent lateral incisor and the canine. In the literature, the treatment of this type of anomaly involves fixed orthodontic appliances. The treatment of the present case, however, was performed with removable appliances. Transposition of the permanent mandibular right lateral incisor and the permanent mandibular right canine was detected in a 12 year old girl. The primary mandibular right canine was extracted to enable the distal movement of the permanent lateral incisor by the eruption force of the permanent canine. The transposed teeth were then aligned in the arch by using removable appliances. The forms of the teeth were changed with each other with composite restorations.