Linear Modeling of Multiple Sclerosis and Its Subgroubs

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Karaca Y., OSMAN O., KARABUDAK R.

TURKISH JOURNAL OF NEUROLOGY, vol.21, no.1, pp.7-12, 2015 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.4274/tnd.82957
  • Journal Name: TURKISH JOURNAL OF NEUROLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.7-12
  • Hacettepe University Affiliated: Yes

Abstract

Objective: In this study, 120 patients diagnosed with clinical multiple sclerosis (MS) of relapsing remitting type (RRMS), secondary progressive type (SPMS) and primary progressive type (PPMS) were examined, as well as 19 healthy subjects. All subjects were between the ages of 20 and 55. Disability levels of MS symptoms were determined using Expanded Disability Status Scale (EDSS). We focused on three regions in the brain, brain stem, periventricular corpus callosum, and upper cervical regions EDSS scores and number of lesions in these three regions are considered as the parameters of the linear mathematical model to determine the subgroups of the disease.