Linear Modeling of Multiple Sclerosis and Its Subgroubs


Karaca Y., OSMAN O., KARABUDAK R.

TURKISH JOURNAL OF NEUROLOGY, vol.21, no.1, pp.7-12, 2015 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.4274/tnd.82957
  • Title of Journal : TURKISH JOURNAL OF NEUROLOGY
  • Page Numbers: pp.7-12

Abstract

Objective: In this study, 120 patients diagnosed with clinical multiple sclerosis (MS) of relapsing remitting type (RRMS), secondary progressive type (SPMS) and primary progressive type (PPMS) were examined, as well as 19 healthy subjects. All subjects were between the ages of 20 and 55. Disability levels of MS symptoms were determined using Expanded Disability Status Scale (EDSS). We focused on three regions in the brain, brain stem, periventricular corpus callosum, and upper cervical regions EDSS scores and number of lesions in these three regions are considered as the parameters of the linear mathematical model to determine the subgroups of the disease.