Increased potassium excretion in children with monosymptomatic nocturnal enuresis: could it be related to Kir 4.1-KCNJ10 gene polymorphism?


Balat A., PARLAK M., OĞUZKAN BALCI S., Gogebakan B., BÜYÜKÇELİK M., Col N., ...Daha Fazla

TURKISH JOURNAL OF PEDIATRICS, cilt.62, sa.2, ss.208-214, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.24953/turkjped.2020.02.006
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Sayfa Sayıları: ss.208-214

Özet

Background and objectives. There are controversial results in the literature regarding urinary electrolytes, especially potassium, in enuretic children. KCNJ10 channel protein, a member of the Kir 4.1 family is expressed in renal distal tubules and has an important function in renal ion transport. We investigated whether KCNJ10 gene polymorphisms are associated with clinical and laboratory findings of a group of Turkish children with monosymptomatic primary nocturnal enuresis (MNE).