Racemic ethyl 4-(2-fluorophenyl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylate

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Atıf İçin Kopyala

Linden A., Safak C., Simsek R.

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, cilt.54, ss.879-882, 1998 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 54
• Basım Tarihi: 1998
• Doi Numarası: 10.1107/s0108270198000195
• Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.879-882
• Hacettepe Üniversitesi Adresli: Evet

Özet

The title compound, C21H24FNO3, has potential calcium modulatory properties. The 1,4-dihydropyridine ring has a shallow boat conformation with the 2-fluorophenyl substituent in an axial synperiplanar orientation. The quinoline ring has a half-chair conformation. Steric interactions between the adjacent methyl and erhoxycarbonyl substituents cause local bond-angle distortions. The molecules are linked into chains by intermolecular N-H ... O hydrogen bonds.