The efficacy of immunoglobulin replacement therapy in the longterm follow-up of the B-cell deficiencies (XLA, HIM, CVID)


Bayrakci B., Ersoy F., Sanal O., Kilic S., Metin A., Tezcan I.

TURKISH JOURNAL OF PEDIATRICS, vol.47, no.3, pp.239-246, 2005 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 3
  • Publication Date: 2005
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.239-246
  • Keywords: immunoglobulin, infection, hospitalization, complication, adverse reaction, COMMON VARIABLE IMMUNODEFICIENCY, DOSE INTRAVENOUS IMMUNOGLOBULIN, X-LINKED AGAMMAGLOBULINEMIA, PRIMARY HYPOGAMMAGLOBULINEMIA, IGM
  • Hacettepe University Affiliated: Yes

Abstract

Immunoglobulin replacement therapy is the essential treatment of B-cell deficiencies. Because of the high expense of therapy, optimal dose, infusion intervals and serum IgG levels should be well defined. Data of 19 X-linked agammaglobulinemia (XLA), 7 hyper-IgM syndrome (HIM) and 20 common variable immunodeficiency (CVID) patients were analyzed.