The efficacy of immunoglobulin replacement therapy in the longterm follow-up of the B-cell deficiencies (XLA, HIM, CVID)

Bayrakci, BENAN; Ersoy, F; Sanal, O; Kilic, S; Metin, A; Tezcan, I

The efficacy of immunoglobulin replacement therapy in the longterm follow-up of the B-cell deficiencies (XLA, HIM, CVID)

Bayrakci B., Ersoy F., Sanal O., Kilic S., Metin A., Tezcan I.

TURKISH JOURNAL OF PEDIATRICS, vol.47, no.3, pp.239-246, 2005 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 47 Issue: 3
Publication Date: 2005
Journal Name: TURKISH JOURNAL OF PEDIATRICS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.239-246
Keywords: immunoglobulin, infection, hospitalization, complication, adverse reaction, COMMON VARIABLE IMMUNODEFICIENCY, DOSE INTRAVENOUS IMMUNOGLOBULIN, X-LINKED AGAMMAGLOBULINEMIA, PRIMARY HYPOGAMMAGLOBULINEMIA, IGM
Hacettepe University Affiliated: Yes

Abstract

Immunoglobulin replacement therapy is the essential treatment of B-cell deficiencies. Because of the high expense of therapy, optimal dose, infusion intervals and serum IgG levels should be well defined. Data of 19 X-linked agammaglobulinemia (XLA), 7 hyper-IgM syndrome (HIM) and 20 common variable immunodeficiency (CVID) patients were analyzed.