Selective inhibition of nitric oxide synthase causes increased muscle thickness in rat esophagus.

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SOYER T. , Boybeyi Ö. , Atasoy P.

Journal of pediatric surgery, cilt.50, sa.7, ss.1112-4, 2015 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Konu: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jpedsurg.2014.10.057
  • Dergi Adı: Journal of pediatric surgery
  • Sayfa Sayıları: ss.1112-4


Aim: Achalasia is a primary motor dysfunction of esophagus which can be created experimentally by nitric oxide synthase (NOS) inhibition. Although several theories have been suggested, mechanism of increased esophageal muscle thickness in achalasia is still unclear. An experimental study was performed to evaluate the esophageal muscle thickness after selective inhibition of NOS in rats.